Adam R. Looker
Vertex Pharmaceuticals (United States)(US)
Publications by Year
Research Areas
Computational Drug Discovery Methods, Innovative Microfluidic and Catalytic Techniques Innovation, Microbial Natural Products and Biosynthesis, Carcinogens and Genotoxicity Assessment, Analytical Chemistry and Chromatography
Most-Cited Works
- → A consortium-driven framework to guide the implementation of ICH M7 Option 4 control strategies(2017)33 cited
- → Risk Assessment of Potentially Genotoxic Impurities within the Framework of Quality by Design(2010)27 cited
- → New Semi-Automated Computer-Based System for Assessing the Purge of Mutagenic Impurities(2019)23 cited
- → Development and Manufacture of the Inosine Monophosphate Dehydrogenase Inhibitor Merimepodib, VX-497(2008)18 cited
- → Understanding the degradation pathway of a poorly water-soluble drug formulated in PEG-400(2006)18 cited
- → Development of a Manufacturing Process for an HCV Protease Inhibitor Candidate Molecule(2014)13 cited
- → Utilizing o-Quinone Methide Chemistry: Synthesis of d9-Ivacaftor(2019)10 cited
- → Optimization of a Hydrogenation Process using Real-Time Mid-IR, Heat Flow and Gas Uptake Measurements(2010)10 cited
- → Case History(2014)7 cited
- → Formation of 9,10-Unsaturation in the Mitomycins: Facile Fragmentation of β-Alkyl-β-aryl-α-oxo-γ-butyrolactones(2000)7 cited