Kevin Parris
Pfizer (United States)(US)
Publications by Year
Research Areas
Chemical Synthesis and Analysis, Computational Drug Discovery Methods, Asymmetric Synthesis and Catalysis, Protein Structure and Dynamics, Analytical Chemistry and Chromatography
Most-Cited Works
- → Crystal structures of substrate binding to Bacillus subtilis holo-(acyl carrier protein) synthase reveal a novel trimeric arrangement of molecules resulting in three active sites(2000)221 cited
- → Molecular recognition with convergent functional groups. VI. Synthetic and structural studies with a model receptor for nucleic acid components(1989)172 cited
- → Discovery of Cytotoxic Dolastatin 10 Analogues with N-Terminal Modifications(2014)131 cited
- → Crystal Structures of a Mutant (βK87T) Tryptophan Synthase α2β2 Complex with Ligands Bound to the Active Sites of the α- and β-Subunits Reveal Ligand-Induced Conformational Changes(1997)124 cited
- → Convergent functional groups: synthetic and structural studies(1985)122 cited
- → Exchange of K+ or Cs+ for Na+ Induces Local and Long-Range Changes in the Three-Dimensional Structure of the Tryptophan Synthase α2β2 Complex(1996)110 cited
- → Convergent functional groups. 4. Recognition and transport of amino acids across a liquid membrane(1987)101 cited
- → Kinetics and mechanism of autoprocessing of human immunodeficiency virus type 1 protease from an analog of the Gag-Pol polyprotein.(1994)98 cited
- → Utilizing Structures of CYP2D6 and BACE1 Complexes To Reduce Risk of Drug–Drug Interactions with a Novel Series of Centrally Efficacious BACE1 Inhibitors(2015)78 cited
- → Highly Potent, Selective, and Orally Active Phosphodiesterase 10A Inhibitors(2011)72 cited