Lawrence J. Breyfogle
Tufts University(US)
Publications by Year
Research Areas
Myeloproliferative Neoplasms: Diagnosis and Treatment, Acute Myeloid Leukemia Research, Chronic Myeloid Leukemia Treatments, RNA Research and Splicing, Eosinophilic Disorders and Syndromes
Most-Cited Works
- → Depletion of Jak2V617F myeloproliferative neoplasm-propagating stem cells by interferon-α in a murine model of polycythemia vera(2013)170 cited
- → Targeting megakaryocytic-induced fibrosis in myeloproliferative neoplasms by AURKA inhibition(2015)140 cited
- → Distinct effects of concomitant Jak2V617F expression and Tet2 loss in mice promote disease progression in myeloproliferative neoplasms(2014)98 cited
- → Csnk1a1 inhibition has p53-dependent therapeutic efficacy in acute myeloid leukemia(2014)93 cited
- → RECQL5 Suppresses Oncogenic JAK2-Induced Replication Stress and Genomic Instability(2015)30 cited
- → JAK2 , CALR , MPL and ASXL1 mutational status correlates with distinct histological features in Philadelphia chromosome-negative myeloproliferative neoplasms(2017)15 cited
- → Flow-Directed Catheters in Hepatic Embolization Therapy—A Review with Clinical Cases(2021)5 cited
- → Aurora A Kinase Is a Novel Therapeutic Target In The Myeloproliferative Neoplasms(2013)3 cited
- → The Recql5 Helicase Is a Novel Downstream Target of Jak2V617F and Maintains Genome Stability in Response to Replication Stress(2014)1 cited
- → Tet2 Loss Accelerates The Myeloproliferative Neoplasm (MPN) Phenotype Of Jak2V617F Knockin Mice But Is Insufficient To Cause Leukemic Transformation(2013)