David S. Millan
Exicure (United States)(US)
Publications by Year
Research Areas
Protein Degradation and Inhibitors, Chromatin Remodeling and Cancer, Crystallization and Solubility Studies, X-ray Diffraction in Crystallography, Synthetic Organic Chemistry Methods
Most-Cited Works
- → Intramolecular hydrogen bonding to improve membrane permeability and absorption in beyond rule of five chemical space(2011)316 cited
- → Total synthesis of (+)-phorboxazole A, a potent cytostatic agent from the sponge Phorbas sp.(2003)100 cited
- → Design and Synthesis of Inhaled p38 Inhibitors for the Treatment of Chronic Obstructive Pulmonary Disease(2011)94 cited
- → Discovery of Clinical Candidate 4-[2-(5-Amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-1,3-thiazol-4-ylbenzenesulfonamide (PF-05089771): Design and Optimization of Diaryl Ether Aryl Sulfonamides as Selective Inhibitors of NaV1.7(2017)83 cited
- → Bromonium Ion Induced Transannular Oxonium Ion Formation−Fragmentation in Model Obtusallene Systems and Structural Reassignment of Obtusallenes V−VII(2009)67 cited
- → Fragment based discovery of a novel and selective PI3 kinase inhibitor(2011)40 cited
- → The Synthesis and Activity of Oxazole and Thiazole Analogues of Urocanic Acid(2000)38 cited
- → A Biosynthetically-Inspired Synthesis of the Tetrahydrofuran Core of Obtusallenes II and IV(2006)36 cited
- → Epimeric Face-Selective Oxidations and Diastereodivergent Transannular Oxonium Ion Formation Fragmentations: Computational Modeling and Total Syntheses of 12-Epoxyobtusallene IV, 12-Epoxyobtusallene II, Obtusallene X, Marilzabicycloallene C, and Marilzabicycloallene D(2016)32 cited
- → What is the Potential for Inhaled P38 Inhibitors in the Treatment of Chronic Obstructive Pulmonary Disease?(2011)23 cited