Martin van der Valk
Publications by Year
Research Areas
Drug Transport and Resistance Mechanisms, Cancer-related Molecular Pathways, Pharmacological Effects and Toxicity Studies, Pharmacogenetics and Drug Metabolism, Genetic factors in colorectal cancer
Most-Cited Works
- → Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer(2001)1,058 cited
- → Requirement for a functional Rb-1 gene in murine development(1992)1,007 cited
- → Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene.(1994)780 cited
- Potent and specific inhibition of the breast cancer resistance protein multidrug transporter in vitro and in mouse intestine by a novel analogue of fumitremorgin C.(2002)
- → Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein(1997)437 cited
- → Conditional biallelic Nf2 mutation in the mouse promotes manifestations of human neurofibromatosis type 2(2000)369 cited
- → Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier(2000)358 cited
- → p107 is a suppressor of retinoblastoma development in pRb-deficient mice(1998)326 cited
- → p15Ink4b is a critical tumour suppressor in the absence of p16Ink4a(2007)268 cited
- → Developmental rescue of an embryonic-lethal mutation in the retinoblastoma gene in chimeric mice.(1994)248 cited