Nicholas J. Pumphrey
Adaptimmune (United Kingdom)(GB)
Publications by Year
Research Areas
CAR-T cell therapy research, Immunotherapy and Immune Responses, Immune Cell Function and Interaction, T-cell and B-cell Immunology, Cancer Immunotherapy and Biomarkers
Most-Cited Works
- → NY-ESO-1–specific TCR–engineered T cells mediate sustained antigen-specific antitumor effects in myeloma(2015)835 cited
- → Identification of a Titin-Derived HLA-A1–Presented Peptide as a Cross-Reactive Target for Engineered MAGE A3–Directed T Cells(2013)661 cited
- → Monoclonal TCR-redirected tumor cell killing(2012)313 cited
- → Human TCR-Binding Affinity is Governed by MHC Class Restriction(2007)206 cited
- → Differential association of cytoplasmic signalling molecules SHP‐1, SHP‐2, SHIP and phospholipase C‐γ1 with PECAM‐1/CD31(1999)102 cited
- → Affinity-enhanced T-cell receptors for adoptive T-cell therapy targeting MAGE-A10: strategy for selection of an optimal candidate(2018)63 cited
- → Tuning T‐Cell Receptor Affinity to Optimize Clinical Risk‐Benefit When Targeting Alpha‐Fetoprotein–Positive Liver Cancer(2018)53 cited
- → Human leucocyte antigen class I-redirected anti-tumour CD4+ T cells require a higher T cell receptor binding affinity for optimal activity than CD8+ T cells(2016)33 cited
- → The Tumor Targeted Superantigen ABR-217620 Selectively Engages TRBV7-9 and Exploits TCR-pMHC Affinity Mimicry in Mediating T Cell Cytotoxicity(2013)28 cited
- Monoclonal TCR-redirected tumor cell killing. Nat Med(2012)