Douglas Macdonald
Tri Alpha Energy (United States)(US)
Publications by Year
Research Areas
Genetic Neurodegenerative Diseases, Mitochondrial Function and Pathology, Neurological disorders and treatments, Muscle Physiology and Disorders, Receptor Mechanisms and Signaling
Most-Cited Works
- → Quantification of mutant huntingtin protein in cerebrospinal fluid from Huntington’s disease patients(2015)259 cited
- → Mutant huntingtin fragmentation in immune cells tracks Huntington’s disease progression(2012)149 cited
- → Position 9 replacement analogs of glucagon uncouple biological activity and receptor binding.(1991)90 cited
- → Molecular Characterization of the Melanin-Concentrating Hormone/Receptor Complex: Identification of Critical Residues Involved in Binding and Activation(2000)87 cited
- → SCH-202676: An Allosteric Modulator of Both Agonist and Antagonist Binding to G Protein-Coupled Receptors(2001)80 cited
- → A Profiling Platform for the Characterization of Transglutaminase 2 (TG2) Inhibitors(2010)74 cited
- → Discovery and Structure–Activity Relationship of Potent and Selective Covalent Inhibitors of Transglutaminase 2 for Huntington’s Disease(2012)69 cited
- → Quantification Assays for Total and Polyglutamine-Expanded Huntingtin Proteins(2014)65 cited
- → Validation of Ultrasensitive Mutant Huntingtin Detection in Human Cerebrospinal Fluid by Single Molecule Counting Immunoassay(2017)61 cited
- → Synthesis and SAR of novel 4,5-diarylimidazolines as potent P2X7 receptor antagonists(2004)55 cited