Rachel Brough
Institute of Cancer Research(GB)Breast Cancer Now(GB)Institute of Cancer Research(CA)CRUK Lung Cancer Centre of Excellence(GB)
Publications by Year
Research Areas
PARP inhibition in cancer therapy, CRISPR and Genetic Engineering, Chromatin Remodeling and Cancer, DNA Repair Mechanisms, Cancer Mechanisms and Therapy
Most-Cited Works
- → DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer(2015)2,165 cited
- → Resistance to therapy caused by intragenic deletion in BRCA2(2008)992 cited
- → The shieldin complex mediates 53BP1-dependent DNA repair(2018)641 cited
- → Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors(2009)629 cited
- → Genome-wide and high-density CRISPR-Cas9 screens identify point mutations in PARP1 causing PARP inhibitor resistance(2018)438 cited
- → ATR inhibitors as a synthetic lethal therapy for tumours deficient in ARID1A(2016)379 cited