Christine E. Arris
AstraZeneca (United Kingdom)(GB)
Publications by Year
Research Areas
Cancer-related Molecular Pathways, HIV/AIDS drug development and treatment, Biochemical and Molecular Research, Protease and Inhibitor Mechanisms, Blood Coagulation and Thrombosis Mechanisms
Most-Cited Works
- → Identification of Novel Purine and Pyrimidine Cyclin-Dependent Kinase Inhibitors with Distinct Molecular Interactions and Tumor Cell Growth Inhibition Profiles(2000)215 cited
- → Structure-based design of a potent purine-based cyclin-dependent kinase inhibitor(2002)212 cited
- → N2-Substituted O6-Cyclohexylmethylguanine Derivatives: Potent Inhibitors of Cyclin-Dependent Kinases 1 and 2(2004)122 cited
- → Probing the ATP Ribose-Binding Domain of Cyclin-Dependent Kinases 1 and 2 withO6-Substituted Guanine Derivatives(2002)84 cited
- → Expression of ADAMTS metalloproteinases in the retinal pigment epithelium derived cell line ARPE-19: transcriptional regulation by TNFα(2003)53 cited
- → 4-Alkoxy-2,6-diaminopyrimidine derivatives: inhibitors of cyclin dependent kinases 1 and 2(2003)53 cited
- → Resistance-Modifying Agents. 8. Inhibition of O6-Alkylguanine-DNA Alkyltransferase by O6-Alkenyl-, O6-Cycloalkenyl-, and O6-(2-Oxoalkyl)guanines and Potentiation of Temozolomide Cytotoxicity in Vitro by O6-(1-Cyclopentenylmethyl)guanine(2000)49 cited
- → Expression of mutant and wild-type TIMP3 in primary gingival fibroblasts from Sorsby's fundus dystrophy patients(2003)24 cited
- → DNA interstrand cross-linking and TP53 status as determinants of tumour cell sensitivity in vitro to the antibody-directed enzyme prodrug therapy ZD2767(2002)21 cited