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Richard D. Dyer | doi.page

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Richard D. Dyer

University of Sudbury(CA)

Publications by Year

Research Areas

Inflammatory mediators and NSAID effects, Synthesis and biological activity, Synthesis and Reactions of Organic Compounds, Geochemistry and Geologic Mapping, Estrogen and related hormone effects

Most-Cited Works

→ 5-lipoxygenase inhibitory activity of zileuton.(1990)419 cited
→ Design of 5-(3,5-di-tert-butyl-4-hydroxyphenyl)-1,3,4-thiadiazoles, -1,3,4-oxadiazoles, and -1,2,4-triazoles as orally active, nonulcerogenic antiinflammatory agents(1993)372 cited
→ Matrix metalloproteinases(1998)271 cited
→ Discovery and Characterization of a Novel Inhibitor of Matrix Metalloprotease-13 That Reduces Cartilage Damage in Vivo without Joint Fibroplasia Side Effects(2007)209 cited
→ 1,3,4-Oxadiazole, 1,3,4-thiadiazole, and 1,2,4-triazole analogs of the fenamates: in vitro inhibition of cyclooxygenase and 5-lipoxygenase activities(1993)202 cited
→ Novel 1,2,4-oxadiazoles and 1,2,4-thiadiazoles as dual 5-lipoxygenase and cyclooxygenase inhibitors(1992)195 cited

→ Attenuation of diet‐induced atherosclerosis in rabbits with a highly selective 15‐lipoxygenase inhibitor lacking significant antioxidant properties(1997)

177 cited

→ Synthesis and biological evaluation of 5-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]oxazoles, -thiazoles, and -imidazoles: novel dual 5-lipoxygenase and cyclooxygenase inhibitors with antiinflammatory activity(1994)162 cited

→ Synthesis, Structure−Activity Relationships, and in Vivo Evaluations of Substituted Di-tert-butylphenols as a Novel Class of Potent, Selective, and Orally Active Cyclooxygenase-2 Inhibitors. 1. Thiazolone and Oxazolone Series(1999)130 cited