Eleanor M. O’Brien
Institute of Cancer Research(GB)
Publications by Year
Research Areas
Microtubule and mitosis dynamics, Epigenetics and DNA Methylation, Cancer-related molecular mechanisms research, DNA Repair Mechanisms, Sarcoma Diagnosis and Treatment
Most-Cited Works
- → Mutations in the DNA methyltransferase gene DNMT3A cause an overgrowth syndrome with intellectual disability(2014)353 cited
- → Aurora A Kinase Inhibition Destabilizes PAX3-FOXO1 and MYCN and Synergizes with Navitoclax to Induce Rhabdomyosarcoma Cell Death(2019)55 cited
- → Small Cajal body-associated RNA 2 (scaRNA2) regulates DNA repair pathway choice by inhibiting DNA-PK(2022)34 cited
- → The long non-coding RNA MYCNOS-01 regulates MYCN protein levels and affects growth of MYCN-amplified rhabdomyosarcoma and neuroblastoma cells(2018)28 cited
- → The Cajal Body Protein WRAP53β Prepares the Scene for Repair of DNA Double-Strand Breaks by Regulating Local Ubiquitination(2019)15 cited
- → Pharmacological EZH2 inhibition combined with retinoic acid treatment promotes differentiation and apoptosis in rhabdomyosarcoma cells(2023)8 cited
- → Impact of Wee1 inhibition on the hypoxia-induced DNA damage response(2013)3 cited
- → Erratum: Corrigendum: Mutations in the DNA methyltransferase gene DNMT3A cause an overgrowth syndrome with intellectual disability(2014)2 cited
- → Combination EZH2 inhibition and retinoic acid treatment promotes differentiation and apoptosis in rhabdomyosarcoma cells(2023)1 cited
- → Supplementary Data from Aurora A Kinase Inhibition Destabilizes PAX3-FOXO1 and MYCN and Synergizes with Navitoclax to Induce Rhabdomyosarcoma Cell Death(2023)