Osamu Kurasawa
Takeda (Japan)(JP)
Publications by Year
Research Areas
Crystallization and Solubility Studies, X-ray Diffraction in Crystallography, DNA and Nucleic Acid Chemistry, Chemical Synthesis and Analysis, Cancer therapeutics and mechanisms
Most-Cited Works
- → Inhibition of GCN2 sensitizes ASNS-low cancer cells to asparaginase by disrupting the amino acid response(2018)164 cited
- → Discovery of a Novel Pyrrole Derivative 1-[5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine Fumarate (TAK-438) as a Potassium-Competitive Acid Blocker (P-CAB)(2012)157 cited
- → Molecular mechanism and potential target indication of TAK-931, a novel CDC7-selective inhibitor(2019)67 cited
- → Discovery, synthesis, and biological evaluation of novel pyrrole derivatives as highly selective potassium-competitive acid blockers(2012)46 cited
- → Identification of Novel, Potent, and Orally Available GCN2 Inhibitors with Type I Half Binding Mode(2019)39 cited
- → CCR5 Antagonists as Anti-HIV-1 Agents. 1. Synthesis and Biological Evaluation of 5-Oxopyrrolidine-3-carboxamide Derivatives(2004)37 cited
- → Synthesis and Properties of Oligonucleotides Having a Phosphorus Chiral Center by Incorporation of Conformationally Rigid 5‘-Cyclouridylic Acid Derivatives(2000)32 cited
- → Discovery of Novel Allosteric Inhibitors of Deoxyhypusine Synthase(2020)30 cited
- → Synthesis and Properties of Oligodeoxynucleotides Incorporating a Conformationally Rigid Uridine Unit Having a Cyclic Structure at the 5‘-Terminal Site(2000)25 cited
- → A CDC7 inhibitor sensitizes DNA-damaging chemotherapies by suppressing homologous recombination repair to delay DNA damage recovery(2021)25 cited