Lise R. Hoth
Pfizer (United States)(US)
Publications by Year
Research Areas
Computational Drug Discovery Methods, Lipoproteins and Cardiovascular Health, Diabetes Treatment and Management, Pancreatic function and diabetes, Metabolism, Diabetes, and Cancer
Most-Cited Works
- → Identification, Characterization, and Crystal Structure of the Omega Class Glutathione Transferases(2000)718 cited
- → Structural and biophysical studies of PCSK9 and its mutants linked to familial hypercholesterolemia(2007)434 cited
- → Crystal structure of cholesteryl ester transfer protein reveals a long tunnel and four bound lipid molecules(2007)271 cited
- → Kinetic analysis of estrogen receptor/ligand interactions(2002)225 cited
- → Spontaneous α-N-6-Phosphogluconoylation of a “His Tag” inEscherichia coli:The Cause of Extra Mass of 258 or 178 Da in Fusion Proteins(1999)215 cited
- → Glutathione S-Transferase Omega 1-1 Is a Target of Cytokine Release Inhibitory Drugs and May Be Responsible for Their Effect on Interleukin-1औ Posttranslational Processing(2003)205 cited
- → Structural Basis for AMPK Activation: Natural and Synthetic Ligands Regulate Kinase Activity from Opposite Poles by Different Molecular Mechanisms(2014)179 cited
- → Crystal structures of interleukin 17A and its complex with IL-17 receptor A(2013)141 cited
- → Introduction of a Crystalline, Shelf-Stable Reagent for the Synthesis of Sulfur(VI) Fluorides(2018)136 cited
- → Covalent Enzyme Inhibition through Fluorosulfate Modification of a Noncatalytic Serine Residue(2017)134 cited