Michael Capparelli
Novartis (United States)(US)
Publications by Year
Research Areas
Oxidative Organic Chemistry Reactions, Signaling Pathways in Disease, Protease and Inhibitor Mechanisms, Electrochemical Analysis and Applications, Histone Deacetylase Inhibitors Research
Most-Cited Works
- → Discovery of CGS 27023A, a Non-Peptidic, Potent, and Orally Active Stromelysin Inhibitor That Blocks Cartilage Degradation in Rabbits(1997)325 cited
- → Small-molecule WNK inhibition regulates cardiovascular and renal function(2016)164 cited
- → Identification of Dipeptidyl Nitriles as Potent and Selective Inhibitors of Cathepsin B through Structure-Based Drug Design(2001)136 cited
- → Discovery of 4-((2 S ,4 S )-4-Ethoxy-1-((5-methoxy-7-methyl-1 H -indol-4-yl)methyl)piperidin-2-yl)benzoic Acid (LNP023), a Factor B Inhibitor Specifically Designed To Be Applicable to Treating a Diverse Array of Complement Mediated Diseases(2020)59 cited
- → A novel kinase inhibitor establishes a predominant role for protein kinase D as a cardiac class IIa histone deacetylase kinase(2009)58 cited
- → Discovery and in Vivo Evaluation of Potent Dual CYP11B2 (Aldosterone Synthase) and CYP11B1 Inhibitors(2013)46 cited
- → Identification of Potent and Selective Amidobipyridyl Inhibitors of Protein Kinase D(2010)41 cited
- → Design and synthesis of an orally active macrocyclic neutral endopeptidase 24.11 inhibitor(1993)32 cited
- → Potent Nonimmunosuppressive Cyclophilin Inhibitors With Improved Pharmaceutical Properties and Decreased Transporter Inhibition(2014)31 cited
- → 3,5-Diarylazoles as novel and selective inhibitors of protein kinase D(2011)28 cited