Tami Annable

Publications by Year

Research Areas

Histone Deacetylase Inhibitors Research, Microtubule and mitosis dynamics, Cancer Treatment and Pharmacology, Liver physiology and pathology, Protein Degradation and Inhibitors

Most-Cited Works

• Reversal of a novel multidrug resistance mechanism in human colon carcinoma cells by fumitremorgin C.(1998)
• → Paclitaxel-resistant cells have a mutation in the paclitaxel-binding region of β-tubulin (Asp26Glu) and less stable microtubules(2006)146 cited
• HTI-286, a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo.(2003)
• → Regulation of Cellular Senescence by miR-34a in Alcoholic Liver Injury(2017)80 cited
• → The let-7/Lin28 axis regulates activation of hepatic stellate cells in alcoholic liver injury(2017)75 cited
• MAC-321, a novel taxane with greater efficacy than paclitaxel and docetaxel in vitro and in vivo.(2003)
• → Tumor Cells Resistant to a Microtubule-Depolymerizing Hemiasterlin Analogue, HTI-286, Have Mutations in α- or β-Tubulin and Increased Microtubule Stability(2004)64 cited
• → 2-(Quinazolin-4-ylamino)-[1,4]benzoquinones as Covalent-Binding, Irreversible Inhibitors of the Kinase Domain of Vascular Endothelial Growth Factor Receptor-2(2005)57 cited
• → Synthesis and Biological Activity of Analogues of the Antimicrotubule AgentN,β,β-Trimethyl-l-phenylalanyl-N-[(1S,2E)-3-carboxy-1-isopropylbut-2-enyl]-N1,3-dimethyl-l-valinamide (HTI-286)(2004)49 cited
• A new antiestrogen, 2-(4-hydroxy-phenyl)-3-methyl-1-[4-(2-piperidin-1-yl-ethoxy)-benzyl]-1H-indol-5-ol hydrochloride (ERA-923), inhibits the growth of tamoxifen-sensitive and -resistant tumors and is devoid of uterotropic effects in mice and rats.(2001)