Liuquan Chang
Pfizer (United States)(US)
Publications by Year
Research Areas
Protein purification and stability, Drug Solubulity and Delivery Systems, Microencapsulation and Drying Processes, Material Dynamics and Properties, Monoclonal and Polyclonal Antibodies Research
Most-Cited Works
- → Mechanism of protein stabilization by sugars during freeze-drying and storage: Native structure preservation, specific interaction, and/or immobilization in a glassy matrix?(2005)446 cited
- → Characterization of the Time Scales of Molecular Motion in Pharmaceutically Important Glasses(1999)336 cited
- → Mechanisms of protein stabilization in the solid state(2009)320 cited
- → Effect of sorbitol and residual moisture on the stability of lyophilized antibodies: Implications for the mechanism of protein stabilization in the solid state(2005)190 cited
- → Nonnative Aggregation of an IgG1 Antibody in Acidic Conditions: Part 1. Unfolding, Colloidal Interactions, and Formation of High-Molecular-Weight Aggregates(2011)123 cited
- → Nonnative Aggregation of an IgG1 Antibody in Acidic Conditions, Part 2: Nucleation and Growth Kinetics with Competing Growth Mechanisms(2011)92 cited
- → Thermophysical Properties of Pharmaceutically Compatible Buffers at Sub-Zero Temperatures: Implications for Freeze-Drying(2002)78 cited
- → Evaluation of glassy-state dynamics from the width of the glass transition: Results from theoretical simulation of differential scanning calorimetry and comparisons with experiment(2004)39 cited
- → Using modulated DSC to investigate the origin of multiple thermal transitions in frozen 10% sucrose solutions(2006)34 cited
- → The Glass Transition and Sub-Tg-Relaxation in Pharmaceutical Powders and Dried Proteins by Thermally Stimulated Current(2008)24 cited