Mark J. Mulvihill
Publications by Year
Research Areas
Growth Hormone and Insulin-like Growth Factors, Cancer, Hypoxia, and Metabolism, Microtubule and mitosis dynamics, Melanoma and MAPK Pathways, Renal cell carcinoma treatment
Most-Cited Works
- → Discovery of OSI-906: A Selective and Orally Efficacious Dual Inhibitor of the IGF-1 Receptor and Insulin Receptor(2009)307 cited
- → Feedback Mechanisms Promote Cooperativity for Small Molecule Inhibitors of Epidermal and Insulin-Like Growth Factor Receptors(2008)209 cited
- → A novel, potent, and selective insulin-like growth factor-I receptor kinase inhibitor blocks insulin-like growth factor-I receptor signaling in vitro and inhibits insulin-like growth factor-I receptor–dependent tumor growth in vivo(2007)147 cited
- → Novel Autotaxin Inhibitor for the Treatment of Idiopathic Pulmonary Fibrosis: A Clinical Candidate Discovered Using DNA-Encoded Chemistry(2020)109 cited
- → A highly effective one-pot synthesis of quinolines from o-nitroarylcarbaldehydes(2006)81 cited
- → Small‐molecule inhibition and activation‐loop trans‐phosphorylation of the IGF1 receptor(2008)80 cited
- → Novel 2-phenylquinolin-7-yl-derived imidazo[1,5-a]pyrazines as potent insulin-like growth factor-I receptor (IGF-IR) inhibitors(2007)72 cited
- → Enzymatic Resolution of Aminocyclopentenols as Precursors to d- and l-Carbocyclic Nucleosides(1998)68 cited
- → Palladium-Catalyzed Direct Heck Arylation of Dual π-Deficient/π-Excessive Heteroaromatics. Synthesis of C-5 Arylated Imidazo[1,5-a]pyrazines(2008)66 cited
- → Small molecule inhibitors of the IGF-1R/IR axis for the treatment of cancer(2011)64 cited