Frank J. Poelwijk
Intarcia Therapeutics (United States)(US)
Publications by Year
Research Areas
Evolution and Genetic Dynamics, Protein Structure and Dynamics, Gene Regulatory Network Analysis, RNA and protein synthesis mechanisms, Microbial Metabolic Engineering and Bioproduction
Most-Cited Works
- → Mutation effects predicted from sequence co-variation(2017)845 cited
- → Empirical fitness landscapes reveal accessible evolutionary paths(2007)591 cited
- → The spatial architecture of protein function and adaptation(2012)473 cited
- → Illuminating protein space with a programmable generative model(2023)361 cited
- → Quantification of the effect of mutations using a global probability model of natural sequence variation(2015)289 cited
- → Reciprocal sign epistasis is a necessary condition for multi-peaked fitness landscapes(2010)233 cited
- → Learning the pattern of epistasis linking genotype and phenotype in a protein(2019)176 cited
- → Inferring protein 3D structure from deep mutation scans(2019)174 cited
- → The Context-Dependence of Mutations: A Linkage of Formalisms(2016)148 cited
- → Tradeoffs and Optimality in the Evolution of Gene Regulation(2011)132 cited