Karen E. Gascoigne
Discovery Centre(CA)
Publications by Year
Research Areas
Protein Degradation and Inhibitors, Prostate Cancer Treatment and Research, Microtubule and mitosis dynamics, CRISPR and Genetic Engineering, Multiple Myeloma Research and Treatments
Most-Cited Works
- → Cancer Cells Display Profound Intra- and Interline Variation following Prolonged Exposure to Antimitotic Drugs(2008)831 cited
- → Enhancer Activity Requires CBP/P300 Bromodomain-Dependent Histone H3K27 Acetylation(2018)408 cited
- → How do anti-mitotic drugs kill cancer cells?(2009)367 cited
- → Induced Ectopic Kinetochore Assembly Bypasses the Requirement for CENP-A Nucleosomes(2011)345 cited
- → Validating Aurora B as an anti-cancer drug target(2006)283 cited
- → CENP-T-W-S-X Forms a Unique Centromeric Chromatin Structure with a Histone-like Fold(2012)271 cited
- → Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity(2019)185 cited
- → Therapeutic Targeting of the CBP/p300 Bromodomain Blocks the Growth of Castration-Resistant Prostate Cancer(2017)149 cited
- → Distinct Organization and Regulation of the Outer Kinetochore KMN Network Downstream of CENP-C and CENP-T(2015)144 cited
- → Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 1: Exploration of Antibody Linker, Payload Loading, and Payload Molecular Properties(2021)144 cited