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Tomohiko Kawate | doi.page

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Tomohiko Kawate

Broad Institute(US)Massachusetts General Hospital(US)Massachusetts Institute of Technology(US)

Publications by Year

Research Areas

Asymmetric Synthesis and Catalysis, Tuberculosis Research and Epidemiology, Axial and Atropisomeric Chirality Synthesis, Coordination Chemistry and Organometallics, Cancer therapeutics and mechanisms

Most-Cited Works

→ Cloning of a yeast 8-oxoguanine DNA glycosylase reveals the existence of a base-excision DNA-repair protein superfamily(1996)436 cited
→ Identification of Novel Inhibitors of M. tuberculosis Growth Using Whole Cell Based High-Throughput Screening(2012)252 cited
→ Large-scale chemical–genetics yields new M. tuberculosis inhibitor classes(2019)175 cited
→ Diarylcoumarins inhibit mycolic acid biosynthesis and kill Mycobacterium tuberculosis by targeting FadD32(2013)95 cited
→ Identification of Novel Inhibitors of Nonreplicating Mycobacterium tuberculosis Using a Carbon Starvation Model(2013)86 cited
→ Chiral Lewis Acid-Mediated Enantioselective Pictet−Spengler Reaction of N_b-Hydroxytryptamine with Aldehydes(1998)84 cited

→ Crystallographic and Functional Studies of Very Short Patch Repair Endonuclease(1999)81 cited

→ Chemical genetics reveals a kinase-independent role for protein kinase R in pyroptosis(2013)77 cited

→ Investigation of the mechanisms of DNA binding of the human G/T glycosylase using designed inhibitors(1997)75 cited

→ Synthesis and structure–activity relationships of phenyl-substituted coumarins with anti-tubercular activity that target FadD32(2013)61 cited