A. Mayweg
Roche (Switzerland)(CH)Roche (China)(CN)
Publications by Year
Research Areas
Protein purification and stability, Crystallization and Solubility Studies, X-ray Diffraction in Crystallography, Hepatitis C virus research, Hepatitis B Virus Studies
Most-Cited Works
- → Structure-Based Design and Synthesis of Potent Cyclic Peptides Inhibiting the YAP–TEAD Protein–Protein Interaction(2014)168 cited
- → β-Secretase (BACE1) Inhibitors with High in Vivo Efficacy Suitable for Clinical Evaluation in Alzheimer’s Disease(2013)136 cited
- → Late-Stage Intermolecular CH Activation for Lead Diversification: A Highly Chemoselective Oxyfunctionalization of the C-9 Position of Potent Bryostatin Analogues(2004)95 cited
- → Discovery of RG7834: The First-in-Class Selective and Orally Available Small Molecule Hepatitis B Virus Expression Inhibitor with Novel Mechanism of Action(2018)73 cited
- → Design and Synthesis of Orally Bioavailable 4-Methyl Heteroaryldihydropyrimidine Based Hepatitis B Virus (HBV) Capsid Inhibitors(2016)72 cited
- → Studies toward the Biomimetic Synthesis of Tropolone Natural Products via a Hetero Diels−Alder Reaction(1999)67 cited
- → Biomimetic Cycloaddition Approach to Tropolone Natural Products via a Tropolone Ortho-quinone Methide(2002)66 cited
- → Discovery and Pre-Clinical Characterization of Third-Generation 4-H Heteroaryldihydropyrimidine (HAP) Analogues as Hepatitis B Virus (HBV) Capsid Inhibitors(2017)58 cited
- → BACE1 inhibitors: A head group scan on a series of amides(2013)52 cited
- → Discovery of 4-Aryl-5,6,7,8-tetrahydroisoquinolines as Potent, Selective, and Orally Active Aldosterone Synthase (CYP11B2) Inhibitors: In Vivo Evaluation in Rodents and Cynomolgus Monkeys(2015)44 cited