Paul D. Donohoue
Publications by Year
Research Areas
CAR-T cell therapy research, CRISPR and Genetic Engineering, Advanced biosensing and bioanalysis techniques, RNA and protein synthesis mechanisms, Biosimilars and Bioanalytical Methods
Most-Cited Works
- → Mapping the genomic landscape of CRISPR–Cas9 cleavage(2017)458 cited
- → Efficient ethanol production from brown macroalgae sugars by a synthetic yeast platform(2013)341 cited
- → Guide RNA Functional Modules Direct Cas9 Activity and Orthogonality(2014)259 cited
- → Advances in Industrial Biotechnology Using CRISPR-Cas Systems(2017)222 cited
- → Structural basis for Cas9 off-target activity(2022)189 cited
- → NmeCas9 is an intrinsically high-fidelity genome-editing platform(2018)132 cited
- → Harnessing type I CRISPR–Cas systems for genome engineering in human cells(2019)121 cited
- → Conformational control of Cas9 by CRISPR hybrid RNA-DNA guides mitigates off-target activity in T cells(2021)62 cited
- → Identification of Formyl Kynurenine Formamidase and Kynurenine Aminotransferase fromSaccharomyces cerevisiaeUsing Crystallographic, Bioinformatic and Biochemical Evidence(2008)55 cited
- → High-Specificity CRISPR-Mediated Genome Engineering in Anti-BCMA Allogeneic CAR T Cells Suppresses Allograft Rejection in Preclinical Models(2024)29 cited