Judi O’Shaughnessy
University of Edinburgh(GB)
Publications by Year
Research Areas
Amyotrophic Lateral Sclerosis Research, Alzheimer's disease research and treatments, Parkinson's Disease Mechanisms and Treatments, Neurogenetic and Muscular Disorders Research, Advanced Fluorescence Microscopy Techniques
Most-Cited Works
- → RNA aptamer reveals nuclear TDP-43 pathology is an early aggregation event that coincides with STMN-2 cryptic splicing and precedes clinical manifestation in ALS(2024)46 cited
- → NLRP3 inflammasome as a key molecular target underlying cognitive resilience in amyotrophic lateral sclerosis(2021)30 cited
- → pTDP‐43 aggregates accumulate in non‐central nervous system tissues prior to symptom onset in amyotrophic lateral sclerosis: a case series linking archival surgical biopsies with clinical phenotypic data(2022)24 cited
- → Two-color coincidence single-molecule pulldown for the specific detection of disease-associated protein aggregates(2023)19 cited
- → Random forest modelling demonstrates microglial and protein misfolding features to be key phenotypic markers in C9orf72 ‐ALS(2022)19 cited
- → Distinct neuroinflammatory signatures exist across genetic and sporadic amyotrophic lateral sclerosis cohorts(2023)15 cited
- → Amygdala TDP-43 pathology is associated with behavioural dysfunction and ferritin accumulation in amyotrophic lateral sclerosis(2024)9 cited
- → Clinicopathological analysis of NEK1 variants in amyotrophic lateral sclerosis(2024)7 cited
- → GLP1 receptor agonism ameliorates Parkinson’s disease through modulation of neuronal insulin signalling and glial suppression(2024)7 cited
- → Exenatide Once Weekly in the Treatment of Patients with Multiple System Atrophy(2025)4 cited