Takayasu Nagahara
Daiichi Sankyo (Germany)(DE)
Publications by Year
Research Areas
Blood Coagulation and Thrombosis Mechanisms, Synthesis of β-Lactam Compounds, Synthesis and Catalytic Reactions, Asymmetric Synthesis and Catalysis, Atrial Fibrillation Management and Outcomes
Most-Cited Works
- → DU‐176b, a potent and orally active factor Xa inhibitor: in vitro and in vivo pharmacological profiles(2008)299 cited
- → Dibasic (Amidinoaryl)propanoic Acid Derivatives as Novel Blood Coagulation Factor Xa Inhibitors(1994)178 cited
- → DX-9065a, a New Synthetic, Potent Anticoagulant and Selective Inhibitor for Factor Xa(1994)153 cited
- → Enantioselective Syntheses of Carbapenem Antibiotics(1987)145 cited
- → Synthesis and Conformational Analysis of a Non-Amidine Factor Xa Inhibitor That Incorporates 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine as S4 Binding Element(2004)70 cited
- → A Novel Factor Xa Inhibitor: Structure-Activity Relationships and Selectivity between Factor Xa and Thrombin(1993)50 cited
- → Design, synthesis, and biological activity of novel factor Xa inhibitors: Improving metabolic stability by S1 and S4 ligand modification(2005)42 cited
- → Chiral synthesis of the key intermediate of (+)- and (-)-thienamycin(1985)33 cited
- → Design, synthesis, and biological activity of non-amidine factor Xa inhibitors containing pyridine N-oxide and 2-carbamoylthiazole units(2004)31 cited
- → Design, synthesis, and biological activity of non-basic compounds as factor Xa inhibitors: SAR study of S1 and aryl binding sites(2005)30 cited