David Hurtado
Proteostasis Therapeutics (United States)(US)
Publications by Year
Research Areas
Neuroscience and Neuropharmacology Research, Alzheimer's disease research and treatments, Ion channel regulation and function, Cellular transport and secretion, Ubiquitin and proteasome pathways
Most-Cited Works
- → The acetylation of tau inhibits its function and promotes pathological tau aggregation(2011)702 cited
- → Aβ Accelerates the Spatiotemporal Progression of Tau Pathology and Augments Tau Amyloidosis in an Alzheimer Mouse Model(2010)224 cited
- → Distinct SNARE complexes mediating membrane fusion in Golgi transport based on combinatorial specificity(2002)203 cited
- → Selectively Silencing GSK-3 Isoforms Reduces Plaques and Tangles in Mouse Models of Alzheimer's Disease(2012)121 cited
- → Identification of an Endoplasmic Reticulum-Retention Motif in an Intracellular Loop of the Kainate Receptor Subunit KA2(2006)66 cited
- → Kainate receptor trafficking: physiological roles and molecular mechanisms(2004)41 cited
- → Trafficking and surface expression of the glutamate receptor subunit, KA2(2003)34 cited
- Selective reduction of GSK-3 isoforms ameliorates pathological signatures of Alzheimer's disease(2011)
- → P3‐351: Small‐molecule inhibition of Usp14 enhances the proteolytic degradation and clearance of misfolded proteins associated with neurodegenerative diseases(2012)
- → S3–02–04: Developing Usp14 inhibitors as disease‐modifying therapeutics for protein aggregation diseases(2013)