Mengkun Zhang
Publications by Year
Research Areas
Microtubule and mitosis dynamics, Cancer-related Molecular Pathways, Cancer Treatment and Pharmacology, Inflammatory mediators and NSAID effects, Ubiquitin and proteasome pathways
Most-Cited Works
- → IL-17 Stimulates the Production and Expression of Proinflammatory Cytokines, IL-β and TNF-α, by Human Macrophages(1998)853 cited
- → Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase(2007)413 cited
- → Characterization of Alisertib (MLN8237), an Investigational Small-Molecule Inhibitor of Aurora A Kinase Using Novel In Vivo Pharmacodynamic Assays(2011)300 cited
- → MLN8054, an Inhibitor of Aurora A Kinase, Induces Senescence in Human Tumor Cells Both In vitro and In vivo(2010)117 cited
- → MLN8054 and Alisertib (MLN8237): Discovery of Selective Oral Aurora A Inhibitors(2015)108 cited
- → Transcriptional induction of cyclooxygenase-2 gene by okadaic acid inhibition of phosphatase activity in human chondrocytes: Co-stimulation of AP-1 and CRE nuclear binding proteins(1998)82 cited
- → Targeting Aurora A kinase activity with the investigational agent alisertib increases the efficacy of cytarabine through a FOXO‐dependent mechanism(2012)52 cited
- → Phase I Assessment of New Mechanism-Based Pharmacodynamic Biomarkers for MLN8054, a Small-Molecule Inhibitor of Aurora A Kinase(2010)46 cited
- → Translational Exposure–Efficacy Modeling to Optimize the Dose and Schedule of Taxanes Combined with the Investigational Aurora A Kinase Inhibitor MLN8237 (Alisertib)(2014)34 cited
- → Enhancement of phosphorylation and transcriptional activity of the glucocorticoid receptor in human synovial fibroblasts by nimesulide, a preferential cyclooxygenase 2 inhibitor(1999)25 cited