Thomas Toneff
University of California San Diego(US)
Publications by Year
Research Areas
Neuropeptides and Animal Physiology, Alzheimer's disease research and treatments, Cellular transport and secretion, Peptidase Inhibition and Analysis, Biochemical and Structural Characterization
Most-Cited Works
- → Cathepsin L in secretory vesicles functions as a prohormone-processing enzyme for production of the enkephalin peptide neurotransmitter(2003)210 cited
- → Inhibition of cathepsin B reduces β-amyloid production in regulated secretory vesicles of neuronal chromaffin cells: evidence for cathepsin B as a candidate β-secretase of Alzheimer's disease(2005)168 cited
- → Tissue-Specific Proteolysis of Huntingtin (htt) in Human Brain: Evidence of Enhanced Levels of N- and C-Terminal htt Fragments in Huntington's Disease Striatum(2001)160 cited
- → Human iPSC Neurons Display Activity-Dependent Neurotransmitter Secretion: Aberrant Catecholamine Levels in Schizophrenia Neurons(2014)108 cited
- → Brain Pyroglutamate Amyloid-β is Produced by Cathepsin B and is Reduced by the Cysteine Protease Inhibitor E64d, Representing a Potential Alzheimer's Disease Therapeutic(2014)83 cited
- → Major Role of Cathepsin L for Producing the Peptide Hormones ACTH, β-Endorphin, and α-MSH, Illustrated by Protease Gene Knockout and Expression(2008)75 cited
- → Formation of the Catecholamine Release-inhibitory Peptide Catestatin from Chromogranin A(2000)75 cited
- → Cathepsin L and Arg/Lys aminopeptidase: a distinct prohormone processing pathway for the biosynthesis of peptide neurotransmitters and hormones(2004)74 cited
- → Obliteration of α‐melanocyte‐stimulating hormone derived from POMC in pituitary and brains of PC2‐deficient mice(2003)56 cited
- → β‐Amyloid peptide in regulated secretory vesicles of chromaffin cells: evidence for multiple cysteine proteolytic activities in distinct pathways for β‐secretase activity in chromaffin vesicles(2002)56 cited