Roxanne Adeline Z. Uy
University of Kansas(US)
Publications by Year
Research Areas
Viral gastroenteritis research and epidemiology, Viral Infections and Immunology Research, Virus-based gene therapy research, Schizophrenia research and treatment, Diabetes, Cardiovascular Risks, and Lipoproteins
Most-Cited Works
- → Design, synthesis, and bioevaluation of viral 3C and 3C-like protease inhibitors(2013)62 cited
- → Structure-Guided Design and Optimization of Dipeptidyl Inhibitors of Norovirus 3CL Protease. Structure–Activity Relationships and Biochemical, X-ray Crystallographic, Cell-Based, and In Vivo Studies(2015)53 cited
- → Inhibition of norovirus 3CL protease by bisulfite adducts of transition state inhibitors(2012)47 cited
- → Macrocyclic inhibitors of 3C and 3C-like proteases of picornavirus, norovirus, and coronavirus(2013)47 cited
- → Potent inhibition of norovirus by dipeptidyl α-hydroxyphosphonate transition state mimics(2013)25 cited
- → Effect of APOE ε4 Genotype on Metabolic Biomarkers in Aging and Alzheimer’s Disease(2017)18 cited
- → 1.60 A resolution structure of Norovirus 3CL protease complex with a covalently bound dipeptidyl inhibitor (1R,2S)-2-({N-[(benzyloxy)carbonyl]-3-cyclohexyl-L-alanyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid (Hexagonal Form)(2014)
- Structure-based design and optimization of dipeptidyl inhibitors of norovirus 3CL protease(2014)
- → 1.85A resolution structure of Norovirus 3CL protease complex with a covalently bound dipeptidyl inhibitor diethyl [(1R,2S)-2-[(N-{[(3-chlorobenzyl)oxy]carbonyl}-3-cyclohexyl-L-alanyl)amino]-1-hydroxy-3-(2-oxo-2H-pyrrol-3-yl)propyl]phosphonate(2014)