David D. Scott
University of Florida(US)
Publications by Year
Research Areas
Amyotrophic Lateral Sclerosis Research, RNA Research and Splicing, Pain Mechanisms and Treatments, Prion Diseases and Protein Misfolding, Neurogenetic and Muscular Disorders Research
Most-Cited Works
- → Structural Insights Into TDP-43 and Effects of Post-translational Modifications(2019)152 cited
- → Small Molecule Targeting TDP-43’s RNA Recognition Motifs Reduces Locomotor Defects in a Drosophila Model of Amyotrophic Lateral Sclerosis (ALS)(2019)67 cited
- → Selective targeting of NaV1.7 via inhibition of the CRMP2-Ubc9 interaction reduces pain in rodents(2021)53 cited
- → The Natural Flavonoid Naringenin Elicits Analgesia through Inhibition of NaV1.8 Voltage-Gated Sodium Channels(2019)47 cited
- → Heat shock protein Grp78/BiP/HspA5 binds directly to TDP-43 and mitigates toxicity associated with disease pathology(2022)38 cited
- → An Allosteric Modulator of RNA Binding Targeting the N-Terminal Domain of TDP-43 Yields Neuroprotective Properties(2020)33 cited
- → Chemical shift perturbation mapping of the Ubc9-CRMP2 interface identifies a pocket in CRMP2 amenable for allosteric modulation of Nav1.7 channels(2018)20 cited
- → Direct targeting of TDP-43, from small molecules to biologics: the therapeutic landscape(2021)17 cited
- → A Chemical Biology Approach to Model Pontocerebellar Hypoplasia Type 1B (PCH1B)(2018)12 cited
- → 1H, 15N and 13C backbone assignment of apo TDP-43 RNA recognition motifs(2019)8 cited