Suchithra Menon
Harvard University(US)Novartis (United States)(US)
Publications by Year
Research Areas
PI3K/AKT/mTOR signaling in cancer, Ubiquitin and proteasome pathways, Autophagy in Disease and Therapy, Tuberous Sclerosis Complex Research, Cancer, Hypoxia, and Metabolism
Most-Cited Works
- → Activation of a Metabolic Gene Regulatory Network Downstream of mTOR Complex 1(2010)1,954 cited
- → Spatial Control of the TSC Complex Integrates Insulin and Nutrient Regulation of mTORC1 at the Lysosome(2014)762 cited
- → Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo(2014)724 cited
- → Akt Stimulates Hepatic SREBP1c and Lipogenesis through Parallel mTORC1-Dependent and Independent Pathways(2011)625 cited
- → TBC1D7 Is a Third Subunit of the TSC1-TSC2 Complex Upstream of mTORC1(2012)610 cited
- → Association of MTOR Mutations With Developmental Brain Disorders, Including Megalencephaly, Focal Cortical Dysplasia, and Pigmentary Mosaicism(2016)275 cited
- → Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis(2013)254 cited
- → Chronic Activation of mTOR Complex 1 Is Sufficient to Cause Hepatocellular Carcinoma in Mice(2012)179 cited
- → The COP9 Signalosome Inhibits p27kip1 Degradation and Impedes G1-S Phase Progression via Deneddylation of SCF Cul1(2002)170 cited
- → Disruption of the COP9 Signalosome Csn2 Subunit in Mice Causes Deficient Cell Proliferation, Accumulation of p53 and Cyclin E, and Early Embryonic Death(2003)142 cited