Diane M. Rush
WuXi AppTec (United States)(US)
Publications by Year
Research Areas
Protein Structure and Dynamics, Alzheimer's disease research and treatments, Computational Drug Discovery Methods, Enzyme Catalysis and Immobilization, Chemical Synthesis and Analysis
Most-Cited Works
- → Identification of a Small Molecule Nonpeptide Active Site β-Secretase Inhibitor That Displays a Nontraditional Binding Mode for Aspartyl Proteases(2004)116 cited
- → BACE-1 inhibition by a series of ψ[CH2NH] reduced amide isosteres(2006)57 cited
- → Discovery of aminoheterocycles as a novel β-secretase inhibitor class: pH dependence on binding activity part 1(2009)57 cited
- → Bicyclic pyridones as potent, efficacious and orally bioavailable thrombin inhibitors(2000)23 cited
- → Identification of Highly Specific Diversity-Oriented Synthesis-Derived Inhibitors of Clostridium difficile(2017)17 cited
- → Synthesis of amicetose by three enantioselective methods(1998)15 cited
- → ChemInform Abstract: Synthesis of Amicetose by Three Enantioselective Methods.(1998)