Manuel Sanclemente
Spanish National Cancer Research Centre(ES)Molecular Oncology (United States)(US)
Publications by Year
Research Areas
Cancer-related Molecular Pathways, Melanoma and MAPK Pathways, Microtubule and mitosis dynamics, Ubiquitin and proteasome pathways, Heat shock proteins research
Most-Cited Works
- → Plk1 overexpression induces chromosomal instability and suppresses tumor development(2018)163 cited
- → Rapid adaptation to CDK2 inhibition exposes intrinsic cell-cycle plasticity(2023)160 cited
- → c-RAF Ablation Induces Regression of Advanced Kras/Trp53 Mutant Lung Adenocarcinomas by a Mechanism Independent of MAPK Signaling(2018)120 cited
- → Structure of the RAF1-HSP90-CDC37 complex reveals the basis of RAF1 regulation(2022)67 cited
- → Comparative proteomics of exosomes secreted by tumoral Jurkat T cells and normal human T cell blasts unravels a potential tumorigenic role for valosin-containing protein(2016)52 cited
- → Kras oncogene ablation prevents resistance in advanced lung adenocarcinomas(2023)46 cited
- → RAF1 kinase activity is dispensable for KRAS/p53 mutant lung tumor progression(2021)33 cited
- → Tumor regression and resistance mechanisms upon CDK4 and RAF1 inactivation in KRAS/P53 mutant lung adenocarcinomas(2020)21 cited
- → Abstract 5992: Cells rapidly adapt to CDK2 inhibitors via plasticity of the CDK2/4/6-Rb-E2F axis(2023)2 cited