Matthew Holderfield
Revolution Medicines (United States)(US)
Publications by Year
Research Areas
Cancer, Hypoxia, and Metabolism, Cancer Research and Treatments, ATP Synthase and ATPases Research, Mechanisms of cancer metastasis, Melanoma and MAPK Pathways
Most-Cited Works
- → Targeting RAF kinases for cancer therapy: BRAF-mutated melanoma and beyond(2014)817 cited
- → TNF primes endothelial cells for angiogenic sprouting by inducing a tip cell phenotype(2008)323 cited
- → Crosstalk Between Vascular Endothelial Growth Factor, Notch, and Transforming Growth Factor-β in Vascular Morphogenesis(2008)318 cited
- → Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy(2024)280 cited
- → Translational and Therapeutic Evaluation of RAS-GTP Inhibition by RMC-6236 in RAS-Driven Cancers(2024)241 cited
- → Cell‐autonomous notch signaling regulates endothelial cell branching and proliferation during vascular tubulogenesis(2005)227 cited
- → K-Ras Promotes Tumorigenicity through Suppression of Non-canonical Wnt Signaling(2015)190 cited
- → Transcriptome-wide characterization of the eIF4A signature highlights plasticity in translation regulation(2014)186 cited
- → Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer(2024)157 cited
- → Mechanism and consequences of RAF kinase activation by small-molecule inhibitors(2014)124 cited