Kristine L. Skele
Johns Hopkins University(US)Genesys (United States)(US)Sidney Kimmel Cancer Center(US)
Publications by Year
Research Areas
Virus-based gene therapy research, PI3K/AKT/mTOR signaling in cancer, Occupational and environmental lung diseases, Animal Virus Infections Studies, Cancer Mechanisms and Therapy
Most-Cited Works
- → AKT and mTOR phosphorylation is frequently detected in ovarian cancer and can be targeted to disrupt ovarian tumor cell growth(2004)419 cited
- → Seneca Valley Virus, a Systemically Deliverable Oncolytic Picornavirus, and the Treatment of Neuroendocrine Cancers(2007)250 cited
- → Positive feedback regulation between AKT activation and fatty acid synthase expression in ovarian carcinoma cells(2005)194 cited
- → The NF2 Tumor Suppressor Gene Product, Merlin, Inhibits Cell Proliferation and Cell Cycle Progression by Repressing Cyclin D1 Expression(2005)174 cited
- → Frequent activation of AKT2 kinase in human pancreatic carcinomas(2002)166 cited
- → Human and mouse mesotheliomas exhibit elevated AKT/PKB activity, which can be targeted pharmacologically to inhibit tumor cell growth(2005)157 cited
- → A Mouse Model Recapitulating Molecular Features of Human Mesothelioma(2005)156 cited
- → 291. In Vivo Characterization of Seneca Valley Virus (SVV-001), a Novel Oncolytic Picornavirus for Systemic Treatment of Patients with Solid Tumors with Neuroendocrine Features(2006)2 cited
- Diminished expression of NF2 in metastatic malignant melanoma(2002)
- → 19 Loss of functional Arf predisposes mice to asbestos-induced mesothelioma(2006)