Paul Balbo
Pfizer (United States)(US)
Publications by Year
Research Areas
RNA Research and Splicing, Enzyme Structure and Function, RNA and protein synthesis mechanisms, Microbial Metabolic Engineering and Bioproduction, Cytokine Signaling Pathways and Interactions
Most-Cited Works
- → Campylobacter jejuni Cytolethal Distending Toxin Causes a G 2 -Phase Cell Cycle Block(1998)254 cited
- → Discovery of a JAK3-Selective Inhibitor: Functional Differentiation of JAK3-Selective Inhibition over pan-JAK or JAK1-Selective Inhibition(2016)189 cited
- → Yersiniabactin from Yersinia pestis: biochemical characterization of the siderophore and its role in iron transport and regulation(1999)176 cited
- → Design of a Janus Kinase 3 (JAK3) Specific Inhibitor 1-((2S,5R)-5-((7H-Pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one (PF-06651600) Allowing for the Interrogation of JAK3 Signaling in Humans(2017)160 cited
- → Mechanism of Poly(A) Polymerase: Structure of the Enzyme-MgATP-RNA Ternary Complex and Kinetic Analysis(2007)91 cited
- → Identification of Cyanamide-Based Janus Kinase 3 (JAK3) Covalent Inhibitors(2018)74 cited
- → The advantages of describing covalent inhibitor in vitro potencies by IC50 at a fixed time point. IC50 determination of covalent inhibitors provides meaningful data to medicinal chemistry for SAR optimization(2020)64 cited
- → Binding site elucidation and structure guided design of macrocyclic IL-17A antagonists(2016)60 cited
- → Structure of Yeast Poly(A) Polymerase in Complex with a Peptide from Fip1, an Intrinsically Disordered Protein(2008)36 cited
- → X-ray Crystallographic and Steady State Fluorescence Characterization of the Protein Dynamics of Yeast Polyadenylate Polymerase(2006)27 cited