Finn P. Holding

Publications by Year

Research Areas

Cancer, Hypoxia, and Metabolism, Amino Acid Enzymes and Metabolism, Mass Spectrometry Techniques and Applications, Monoclonal and Polyclonal Antibodies Research, Glycosylation and Glycoproteins Research

Most-Cited Works

• → Serine is a natural ligand and allosteric activator of pyruvate kinase M2(2012)654 cited
• → Crystal structure of human CDK4 in complex with a D-type cyclin(2009)226 cited
• → Structure of the Epigenetic Oncogene MMSET and Inhibition by N-Alkyl Sinefungin Derivatives(2016)67 cited
• → A prototype methodology combining surface‐enhanced laser desorption/ionization protein chip technology and artificial neural network algorithms to predict the chemoresponsiveness of breast cancer cell lines exposed to Paclitaxel and Doxorubicin under in vitro conditions(2003)63 cited
• → Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA₂) Discovered through X-ray Fragment Screening(2016)23 cited
• → In-gel activity-based protein profiling of a clickable covalent ERK1/2 inhibitor(2016)22 cited
• → Native Mass Spectrometry Gives Insight into the Allosteric Binding Mechanism of M2 Pyruvate Kinase to Fructose-1,6-Bisphosphate(2018)20 cited
• → Application of Native ESI-MS to Characterize Interactions between Compounds Derived from Fragment-Based Discovery Campaigns and Two Pharmaceutically Relevant Proteins(2018)18 cited
• → Fragment-Based Discovery of a Series of Allosteric-Binding Site Modulators of β-Glucocerebrosidase(2024)8 cited
• → High-Throughput Identification and Characterization of LptDE-Binding Bicycle Peptides Using Phage Display and Cryo-EM(2025)1 cited