Vera Grinkevich
Babraham Institute(GB)
Publications by Year
Research Areas
HER2/EGFR in Cancer Research, DNA Repair Mechanisms, Cancer-related Molecular Pathways, Melanoma and MAPK Pathways, Protein Tyrosine Phosphatases
Most-Cited Works
- → A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia(2016)815 cited
- → Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance(2021)340 cited
- → The structure of p53 tumour suppressor protein reveals the basis for its functional plasticity(2006)127 cited
- → Inhibition of Glycolytic Enzymes Mediated by Pharmacologically Activated p53(2011)124 cited
- → Ablation of Key Oncogenic Pathways by RITA-Reactivated p53 Is Required for Efficient Apoptosis(2009)123 cited
- → POLQ seals post-replicative ssDNA gaps to maintain genome stability in BRCA-deficient cancer cells(2022)120 cited
- → Rescue of the apoptotic-inducing function of mutant p53 by small molecule RITA(2010)78 cited
- → Abrogation of Wip1 expression by RITA-activated p53 potentiates apoptosis induction via activation of ATM and inhibition of HdmX(2011)43 cited
- → Discovery, Characterization, and Structure-Based Optimization of Small-Molecule In Vitro and In Vivo Probes for Human DNA Polymerase Theta(2022)42 cited
- → Small-Molecule Polθ Inhibitors Provide Safe and Effective Tumor Radiosensitization in Preclinical Models(2023)32 cited