Karen Haggerty
Newcastle University(GB)
Publications by Year
Research Areas
Cancer-related Molecular Pathways, Crystallization and Solubility Studies, X-ray Diffraction in Crystallography, HIV/AIDS drug development and treatment, Crystallography and molecular interactions
Most-Cited Works
- → Isoindolinone Inhibitors of the Murine Double Minute 2 (MDM2)-p53 Protein−Protein Interaction: Structure−Activity Studies Leading to Improved Potency(2011)144 cited
- → Structure-Based Design of Potent and Orally Active Isoindolinone Inhibitors of MDM2-p53 Protein–Protein Interaction(2021)52 cited
- → MDM2-p53 protein–protein interaction inhibitors: A-ring substituted isoindolinones(2011)44 cited
- → Axially chiral BODIPYs(2014)40 cited
- → Synthesis and biological evaluation of 5-substituted O4-alkylpyrimidines as CDK2 inhibitors(2010)28 cited
- → Potent enantioselective inhibition of DNA-dependent protein kinase (DNA-PK) by atropisomeric chromenone derivatives(2012)26 cited
- → 8-Substituted O6-Cyclohexylmethylguanine CDK2 Inhibitors: Using Structure-Based Inhibitor Design to Optimize an Alternative Binding Mode(2013)23 cited
- → Structure-based design of 2-arylamino-4-cyclohexylmethoxy-5-nitroso-6-aminopyrimidine inhibitors of cyclin-dependent kinase 2(2007)17 cited
- → Atropisomeric 8-arylchromen-4-ones exhibit enantioselective inhibition of the DNA-dependent protein kinase (DNA-PK)(2010)16 cited
- Identification of potent water-soluble DNA-dependent protein kinase (DNA-PK) inhibitors using a small-molecule library approach [abstract](2008)