Tomohiro Ohashi
Takeda (Japan)(JP)
Publications by Year
Research Areas
Hedgehog Signaling Pathway Studies, Epigenetics and DNA Methylation, Cancer-related Molecular Pathways, Crystallization and Solubility Studies, X-ray Diffraction in Crystallography
Most-Cited Works
- → CLK-dependent exon recognition and conjoined gene formation revealed with a novel small molecule inhibitor(2017)136 cited
- → Design and Synthesis of Novel DFG-Out RAF/Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Inhibitors. 1. Exploration of [5,6]-Fused Bicyclic Scaffolds(2012)77 cited
- → Design and synthesis of novel pyrimido[4,5-b]azepine derivatives as HER2/EGFR dual inhibitors(2013)73 cited
- → Discovery of the investigational drug TAK-441, a pyrrolo[3,2-c]pyridine derivative, as a highly potent and orally active hedgehog signaling inhibitor: Modification of the core skeleton for improved solubility(2012)71 cited
- → Discovery of pyrrolo[3,2-c]quinoline-4-one derivatives as novel hedgehog signaling inhibitors(2012)64 cited
- → Impact of renal function on coronary plaque composition(2009)61 cited
- → Design and Synthesis of Pyrrolo[3,2-d]pyrimidine Human Epidermal Growth Factor Receptor 2 (HER2)/Epidermal Growth Factor Receptor (EGFR) Dual Inhibitors: Exploration of Novel Back-Pocket Binders(2012)43 cited
- → Efficacy and safety of radiofrequency catheter ablation for atrial fibrillation in chronic hemodialysis patients(2013)26 cited
- → Synthetic Studies of Norzoanthamine. Preparation of the Diene-yne-diene Precursor of an ABC-ring Fragment(2005)18 cited
- → Healthcare-Associated Pneumonia among Hospitalized Patients in a Japanese Community Hospital.(2009)16 cited