Gordon S. Currie
AstraZeneca (United Kingdom)(GB)
Publications by Year
Research Areas
Catalytic C–H Functionalization Methods, Asymmetric Synthesis and Catalysis, PI3K/AKT/mTOR signaling in cancer, Cyclopropane Reaction Mechanisms, Sulfur-Based Synthesis Techniques
Most-Cited Works
- → Discovery of a Potent and Selective EGFR Inhibitor (AZD9291) of Both Sensitizing and T790M Resistance Mutations That Spares the Wild Type Form of the Receptor(2014)591 cited
- → Discovery of 4-Amino-N-[(1S)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide (AZD5363), an Orally Bioavailable, Potent Inhibitor of Akt Kinases(2013)213 cited
- → Optimization of a Novel Binding Motif to (E)-3-(3,5-Difluoro-4-((1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)phenyl)acrylic Acid (AZD9496), a Potent and Orally Bioavailable Selective Estrogen Receptor Downregulator and Antagonist(2015)159 cited
- → Catalytic Enantioselective Intermolecular Hydroacylation: Rhodium-Catalyzed Combination of β-S-Aldehydes and 1,3-Disubstituted Allenes(2008)154 cited
- → Chelation-Controlled Intermolecular Alkene and Alkyne Hydroacylation: The Utility of β-Thioacetal Aldehydes(2005)77 cited
- → Rhodium-Catalyzed Intermolecular Chelation Controlled Alkene and Alkyne Hydroacylation: Synthetic Scope of β-S-Substituted Aldehyde Substrates(2006)75 cited
- → Discovery, synthesis and biological evaluation of novel glucokinase activators(2005)54 cited
- → Asymmetry in the boronic acid Mannich reaction: diastereocontrolled addition to chiral iminium species derived from aldehydes and (S)-5-phenylmorpholin-2-one(1996)48 cited
- → Intermolecular rhodium catalyzed hydroacylation of allenes: the regioselective synthesis of β,γ-unsaturated ketones(2009)38 cited
- → Chirally templated boronic acid Mannich reaction in the synthesis of optically active α-amino acids(2000)37 cited