Dan Lohse
Retriev Technologies (United States)(US)
Publications by Year
Research Areas
Chronic Myeloid Leukemia Treatments, Quinazolinone synthesis and applications, Protein Kinase Regulation and GTPase Signaling, Chronic Lymphocytic Leukemia Research, Myeloproliferative Neoplasms: Diagnosis and Treatment
Most-Cited Works
- → Design and Selection of Toca 511 for Clinical Use: Modified Retroviral Replicating Vector With Improved Stability and Gene Expression(2012)138 cited
- → Discovery of 3,3‘-(2,4-Diaminopteridine-6,7-diyl)diphenol as an Isozyme-Selective Inhibitor of PI3K for the Treatment of Ischemia Reperfusion Injury Associated with Myocardial Infarction(2007)55 cited
- → Discovery of [7-(2,6-dichlorophenyl)-5-methylbenzo [1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-ylethoxy)phenyl]amine—a potent, orally active Src kinase inhibitor with anti-tumor activity in preclinical assays(2006)47 cited
- → Development of Prodrug 4-Chloro-3-(5-methyl-3-{[4-(2-pyrrolidin-1-ylethoxy)phenyl]amino}-1,2,4-benzotriazin-7-yl)phenyl Benzoate (TG100801): A Topically Administered Therapeutic Candidate in Clinical Trials for the Treatment of Age-Related Macular Degeneration(2008)44 cited
- → Inhibitors of ABL and the ABL-T315I Mutation(2008)41 cited
- → Discovery and preliminary structure–activity relationship studies of novel benzotriazine based compounds as Src inhibitors(2006)28 cited
- → The design and preliminary structure–activity relationship studies of benzotriazines as potent inhibitors of Abl and Abl-T315I enzymes(2007)24 cited
- → TG101348: A Dual-Acting JAK2/FLT3 Small Molecule Kinase Inhibitor for the Treatment of AML.(2007)3 cited
- → JAK2 Inhibitors for the Treatment of Myeloprolifertive Disorders.(2006)3 cited
- → In Vitro and In Vivo Inhibition of the T315I Mutant BCR/ABL Kinase.(2006)3 cited