Keith Hoffmaster
Publications by Year
Research Areas
Drug Transport and Resistance Mechanisms, Monoclonal and Polyclonal Antibodies Research, Mast cells and histamine, HER2/EGFR in Cancer Research, Pharmacogenetics and Drug Metabolism
Most-Cited Works
- → Membrane transporters in drug development(2010)3,297 cited
- → In Vitro Methods to Support Transporter Evaluation in Drug Discovery and Development(2013)262 cited
- → Integration of hepatic drug transporters and phase II metabolizing enzymes: Mechanisms of hepatic excretion of sulfate, glucuronide, and glutathione metabolites(2006)247 cited
- → Implementation of pharmacokinetic and pharmacodynamic strategies in early research phases of drug discovery and development at Novartis Institute of Biomedical Research(2014)224 cited
- → SHP2 inhibition restores sensitivity in ALK-rearranged non-small-cell lung cancer resistant to ALK inhibitors(2018)200 cited
- → Inhibition of Dengue Virus through Suppression of Host Pyrimidine Biosynthesis(2011)162 cited
- → Liver tissue engineering in the evaluation of drug safety(2009)155 cited
- → P-glycoprotein Expression, Localization, and Function in Sandwich-Cultured Primary Rat and Human Hepatocytes: Relevance to the Hepatobiliary Disposition of a Model Opioid Peptide(2004)153 cited
- → Discovery of Small Molecule Splicing Modulators of Survival Motor Neuron-2 (SMN2) for the Treatment of Spinal Muscular Atrophy (SMA)(2018)131 cited
- → Identification of broad-spectrum antiviral compounds and assessment of the druggability of their target for efficacy against respiratory syncytial virus (RSV)(2011)94 cited