Nicolas Szapiel
Bristol-Myers Squibb (Germany)(DE)Bristol-Myers Squibb (Sweden)(SE)
Publications by Year
Research Areas
Protein Kinase Regulation and GTPase Signaling, Wnt/β-catenin signaling in development and cancer, Receptor Mechanisms and Signaling, Melanoma and MAPK Pathways, Alzheimer's disease research and treatments
Most-Cited Works
- → Profiling of host cell proteins by two‐dimensional difference gel electrophoresis (2D‐DIGE): Implications for downstream process development(2009)171 cited
- → Discovery of new acylaminopyridines as GSK-3 inhibitors by a structure guided in-depth exploration of chemical space around a pyrrolopyridinone core(2015)116 cited
- → Design, Structure–Activity Relationships, and In Vivo Evaluation of Potent and Brain-Penetrant Imidazo[1,2-b]pyridazines as Glycogen Synthase Kinase-3β (GSK-3β) Inhibitors(2023)29 cited
- → Discovery of Pyridazinone and Pyrazolo[1,5-a]pyridine Inhibitors of C-Terminal Src Kinase(2019)26 cited
- → Discovery of 2-(Anilino)pyrimidine-4-carboxamides as Highly Potent, Selective, and Orally Active Glycogen Synthase Kinase-3 (GSK-3) Inhibitors(2023)17 cited
- → Genetic interaction network of the Saccharomyces cerevisiae type 1 phosphatase Glc7(2008)16 cited
- → An improved protocol for amino acid type-selective isotope labeling in insect cells(2017)8 cited
- → Exploration of macrocyclic peptide binders to the extracellular CRD domain of human receptor tyrosine kinase-like orphan receptor 1 (ROR1)(2023)6 cited
- → Ultrasensitive Quantitative LC–MS/MS of an Inhibitor of Apoptosis Protein’s Antagonist in Plasma Using Protein Target Affinity Extraction(2016)4 cited
- → Covalent inhibitor design confers activity against both GDP- and GTP-bound forms of KRAS G12C(2026)2 cited