Edward Hurrell
Heptares Therapeutics (United Kingdom)(GB)
Publications by Year
Research Areas
Receptor Mechanisms and Signaling, Adenosine and Purinergic Signaling, Enterobacteriaceae and Cronobacter Research, Antibiotic Resistance in Bacteria, Neuropeptides and Animal Physiology
Most-Cited Works
- → Structure of the Adenosine A2A Receptor in Complex with ZM241385 and the Xanthines XAC and Caffeine(2011)548 cited
- → Discovery of 1,2,4-Triazine Derivatives as Adenosine A2A Antagonists using Structure Based Drug Design(2012)302 cited
- → The properties of thermostabilised G protein-coupled receptors (StaRs) and their use in drug discovery(2010)158 cited
- → Neonatal enteral feeding tubes as loci for colonisation by members of the Enterobacteriaceae(2009)139 cited
- → Identification of Novel Adenosine A2A Receptor Antagonists by Virtual Screening(2012)135 cited
- → Virulence studies of Enterobacter sakazakiiisolates associated with a neonatal intensive care unit outbreak(2008)129 cited
- → Enterobacter sakazakii invades brain capillary endothelial cells, persists in human macrophages influencing cytokine secretion and induces severe brain pathology in the neonatal rat(2007)126 cited
- → Biofilm formation on enteral feeding tubes by Cronobacter sakazakii, Salmonella serovars and other Enterobacteriaceae(2009)103 cited
- → Small molecule AZD4635 inhibitor of A2AR signaling rescues immune cell function including CD103+ dendritic cells enhancing anti-tumor immunity(2020)97 cited
- → From structure to clinic: Design of a muscarinic M1 receptor agonist with the potential to treat Alzheimer’s disease(2021)89 cited