Kristopher M. Depew
Agios Pharmaceuticals (United States)(US)
Publications by Year
Research Areas
Synthetic Organic Chemistry Methods, Carbohydrate Chemistry and Synthesis, Microbial Natural Products and Biosynthesis, Chemical Synthesis and Analysis, Asymmetric Synthesis and Catalysis
Most-Cited Works
- → Total Synthesis of 5-N-Acetylardeemin and Amauromine: Practical Routes to Potential MDR Reversal Agents(1999)245 cited
- → Small-Molecule Microarrays: Covalent Attachment and Screening of Alcohol-Containing Small Molecules on Glass Slides(2000)184 cited
- → Total Synthesis of Gypsetin, Deoxybrevianamide E, Brevianamide E, and Tryprostatin B: Novel Constructions of 2,3-Disubstituted Indoles(1999)183 cited
- → Discovery and development of Hsp90 inhibitors: a promising pathway for cancer therapy(2010)176 cited
- → Stereoselective Total Syntheses of Amauromine and 5-N-Acetylardeemin. A Concise Route to the Family of "Reverse-Prenylated" Hexahydropyrroloindole Alkaloids(1994)173 cited
- → Total Synthesis of Tryprostatin B: Generation of a Nucleophilic Prenylating Species from a Prenylstannane(1996)84 cited
- → Reversal of anticancer multidrug resistance by the ardeemins(1998)66 cited
- → Pathway Development and Pilot Library Realization in Diversity-Oriented Synthesis(2002)60 cited
- → Synthesis and a Preliminary DNA Binding Study of Hybrids of the Carbohydrate Domain of Calicheamicin γ and the Aglycone of Daunorubicin: Calichearubicins A and B(1996)34 cited
- → Simultaneous determination of helical unwinding angles and intrinsic association constants in ligand–DNA complexes: The interaction between DNA and calichearubicin B(1998)27 cited