Dos D. Sarbassov
Nazarbayev University(KZ)
Publications by Year
Research Areas
PI3K/AKT/mTOR signaling in cancer, Protein Kinase Regulation and GTPase Signaling, FOXO transcription factor regulation, Ubiquitin and proteasome pathways, Metabolism, Diabetes, and Cancer
Most-Cited Works
- → Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR Complex(2005)6,146 cited
- → mTOR Interacts with Raptor to Form a Nutrient-Sensitive Complex that Signals to the Cell Growth Machinery(2002)2,961 cited
- → Rictor, a Novel Binding Partner of mTOR, Defines a Rapamycin-Insensitive and Raptor-Independent Pathway that Regulates the Cytoskeleton(2004)2,646 cited
- → Prolonged Rapamycin Treatment Inhibits mTORC2 Assembly and Akt/PKB(2006)2,633 cited
- → Growing roles for the mTOR pathway(2005)1,547 cited
- → GβL, a Positive Regulator of the Rapamycin-Sensitive Pathway Required for the Nutrient-Sensitive Interaction between Raptor and mTOR(2003)948 cited
- → The Skp2-SCF E3 Ligase Regulates Akt Ubiquitination, Glycolysis, Herceptin Sensitivity, and Tumorigenesis(2012)461 cited
- → Rapamycin derivatives reduce mTORC2 signaling and inhibit AKT activation in AML(2006)342 cited
- → Redox Regulation of the Nutrient-sensitive Raptor-mTOR Pathway and Complex(2005)245 cited
- → ATF4 induction through an atypical integrated stress response to ONC201 triggers p53-independent apoptosis in hematological malignancies(2016)199 cited