Jacqueline J.L. Jacobs
The Netherlands Cancer Institute(NL)Oncode Institute(NL)
Publications by Year
Research Areas
DNA Repair Mechanisms, Telomeres, Telomerase, and Senescence, Epigenetics and DNA Methylation, Genomics and Chromatin Dynamics, CRISPR and Genetic Engineering
Most-Cited Works
- → The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus(1999)1,558 cited
- → Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF(1999)1,069 cited
- → Control of the Replicative Life Span of Human Fibroblasts by p16 and the Polycomb Protein Bmi-1(2002)426 cited
- → Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells(2018)412 cited
- → Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19ARF) and is amplified in a subset of human breast cancers(2000)369 cited
- The Bmi-1 oncogene induces telomerase activity and immortalizes human mammary epithelial cells.(2002)
- → Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice(2005)