Nobuyuki Negoro
Takeda (Japan)(JP)
Publications by Year
Research Areas
Diabetes Treatment and Management, Catalytic C–H Functionalization Methods, Pancreatic function and diabetes, Kawasaki Disease and Coronary Complications, Receptor Mechanisms and Signaling
Most-Cited Works
- → Discovery of TAK-875: A Potent, Selective, and Orally Bioavailable GPR40 Agonist(2010)247 cited
- → TAK-875, an Orally Available G Protein-Coupled Receptor 40/Free Fatty Acid Receptor 1 Agonist, Enhances Glucose-Dependent Insulin Secretion and Improves Both Postprandial and Fasting Hyperglycemia in Type 2 Diabetic Rats(2011)145 cited
- → Angiotensin Receptor-1 Blocker Inhibits Atherosclerotic Changes and Endothelial Disruption of the Aortic Valve in Hypercholesterolemic Rabbits(2007)134 cited
- → Design, Synthesis, and Biological Activity of Potent and Orally Available G Protein-Coupled Receptor 40 Agonists(2011)87 cited
- → Simple and Useful Tests for Discriminating Between Acute Aortic Dissection of the Ascending Aorta and Acute Myocardial Infarction in the Emergency Setting(2005)77 cited
- → Optimization of (2,3-Dihydro-1-benzofuran-3-yl)acetic Acids: Discovery of a Non-Free Fatty Acid-Like, Highly Bioavailable G Protein-Coupled Receptor 40/Free Fatty Acid Receptor 1 Agonist as a Glucose-Dependent Insulinotropic Agent(2012)73 cited
- → Young Adult Patients With Short Dissection Length and Thrombosed False Lumen Without Ulcer-Like Projections are Liable to Have False-Negative Results of D-Dimer Testing for Acute Aortic Dissection Based on a Study of 113 Cases(2006)69 cited
- → Reductive coupling of carbonyl compounds to pinacols by using SmI2MeOH or SmI2Ti(OiPr)4MeOH systems(1997)67 cited
- → Reductive dehalogenation of aliphatic vic-dihalides with metallic samarium in a methanolic medium(1996)67 cited
- → Identification of Fused-Ring Alkanoic Acids with Improved Pharmacokinetic Profiles that Act as G Protein-Coupled Receptor 40/Free Fatty Acid Receptor 1 Agonists(2012)64 cited