Frédéric H. Vaillancourt
C4 Therapeutics (United States)(US)
Publications by Year
Research Areas
Click Chemistry and Applications, Metal-Catalyzed Oxygenation Mechanisms, Estrogen and related hormone effects, Microbial bioremediation and biosurfactants, Computational Drug Discovery Methods
Most-Cited Works
- → Nature's Inventory of Halogenation Catalysts: Oxidative Strategies Predominate(2006)541 cited
- → The Ins and Outs of Ring-Cleaving Dioxygenases(2006)429 cited
- → Crystal structure of the non-haem iron halogenase SyrB2 in syringomycin biosynthesis(2006)393 cited
- → SyrB2 in syringomycin E biosynthesis is a nonheme Fe II α-ketoglutarate- and O 2 -dependent halogenase(2005)330 cited
- → Cryptic chlorination by a non-haem iron enzyme during cyclopropyl amino acid biosynthesis(2005)319 cited
- → Substrate-Triggered Formation and Remarkable Stability of the C−H Bond-Cleaving Chloroferryl Intermediate in the Aliphatic Halogenase, SyrB2(2009)247 cited
- → Halogenation of Unactivated Carbon Centers in Natural Product Biosynthesis: Trichlorination of Leucine during Barbamide Biosynthesis(2006)189 cited
- → Generation of D Amino Acid Residues in Assembly of Arthrofactin by Dual Condensation/Epimerization Domains(2005)160 cited
- → Identification of a lipid kinase as a host factor involved in hepatitis C virus RNA replication(2009)145 cited
- → The Mechanism-based Inactivation of 2,3-Dihydroxybiphenyl 1,2-Dioxygenase by Catecholic Substrates(2002)125 cited