D.O. Somers
GlaxoSmithKline (United Kingdom)(GB)
Publications by Year
Research Areas
HIV/AIDS drug development and treatment, Melanoma and MAPK Pathways, Biochemical and Molecular Research, Enzyme Structure and Function, HIV Research and Treatment
Most-Cited Works
- → High resolution structures of HIV-1 RT from four RT–inhibitor complexes(1995)498 cited
- → Crystal structure of the anti-bacterial sulfonamide drug target dihydropteroate synthase(1997)291 cited
- → CSAR 2014: A Benchmark Exercise Using Unpublished Data from Pharma(2016)108 cited
- → N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)amides as potent, selective, inhibitors of JNK2 and JNK3(2006)90 cited
- → Crystals of HIV-1 Reverse Transcriptase Diffracting to 2·2 Å Resolution(1994)60 cited
- → Discovery of GSK143, a highly potent, selective and orally efficacious spleen tyrosine kinase inhibitor(2011)54 cited
- → 2.0 Å X‐ray structure of the ternary complex of 7,8‐dihydro‐6‐hydroxymethylpterinpyrophosphokinase from Escherichia coli with ATP and a substrate analogue(1999)50 cited
- → Continuous and Discontinuous Changes in the Unit Cell of HIV-1 Reverse Transcriptase Crystals on Dehydration(1998)50 cited
- → Discovery and Optimization of Potent, Selective, and in Vivo Efficacious 2-Aryl Benzimidazole BCATm Inhibitors(2016)44 cited
- → p38α Mitogen-Activated Protein Kinase Inhibitors: Optimization of a Series of Biphenylamides to Give a Molecule Suitable for Clinical Progression(2009)44 cited